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Nerolidol

Terpene
Terpene

Nerolidol

A woody, floral terpene found in cannabis and jasmine, associated with calming properties and enhanced skin absorption.

Nerolidol is a woody, floral sesquiterpene found in cannabis, jasmine, ginger, tea tree, and neroli (orange blossom). It comes in two forms: trans-nerolidol and cis-nerolidol. This terpene produces a complex aroma that blends fresh bark, flowers, and subtle citrus notes.

Research and Properties

Nerolidol has been studied for several noteworthy properties. Research suggests it can enhance skin penetration of other compounds, making it valuable in transdermal and topical formulations. Studies have also explored anti-parasitic, antifungal, and antimicrobial effects. A study published in Parasitology Research found nerolidol effective against Leishmania parasites. Additionally, nerolidol has shown sedative properties in animal studies, suggesting it may contribute to the calming effects of certain cannabis strains.

Cannabis Applications

Nerolidol appears in strains like Jack Herer, Skywalker OG, Island Sweet Skunk, and Sweet Skunk. Its skin-penetrating properties make it particularly relevant for cannabis topicals and transdermal products, where improved absorption can enhance effectiveness. In smoked or vaporized cannabis, nerolidol adds a sophisticated woody-floral note to the flavor profile.

Frequently Asked Questions

What does Nerolidol smell and taste like?
Nerolidol has a woody, floral aroma with notes of fresh bark and citrus. It is found in ginger, jasmine, and tea tree, giving it a complex, layered scent profile.
What effects is Nerolidol associated with?
Nerolidol is associated with relaxing, sedative effects. Research has explored its potential antifungal, antiparasitic, and antimicrobial properties. It may also enhance the absorption of other compounds through the skin.
Which cannabis strains are high in Nerolidol?
Strains high in nerolidol typically feature its signature aroma prominently. Lab-tested terpene profiles on product labels can help you identify strains with elevated nerolidol content. Ask your budtender or check strain databases for terpene-specific recommendations.
Is Nerolidol found in other plants besides cannabis?
Yes, nerolidol is found in various plants, fruits, and herbs beyond cannabis. Terpenes are among the most common organic compounds in nature, produced by many plant species for protection, pollination, and signaling. The shared terpenes between cannabis and everyday plants explain why certain strains remind people of familiar scents.
Does Nerolidol contribute to the entourage effect?
Yes, nerolidol is believed to contribute to the entourage effect, where terpenes and cannabinoids work together to shape the overall cannabis experience. Research suggests terpenes like nerolidol may modulate how cannabinoids interact with receptors, potentially influencing the intensity and character of effects.